Transaminases are one of the enzymes that we can find in the liver. Its values are very important because they indicate some diseases that affect this organ and that can become serious. However, sometimes, the values are altered as can happen in pregnancy.
Then,what are the normal values of transaminases? In oneHOWTO we are going to explain what these enzymes consist of, their types and their correct levels, as well as their relationship with diseases.
What are transaminases
As we have indicated previously, transaminases are enzymes that are mainly present in the liver, which is the organ that produces them. However, they can also be in the kidneys, muscles, or brain. Their levels show up in blood tests. In this way, an analytic indicates if they are low, high or if the person is within the normal transaminase parameters.
Depending on the results of the analysis, it may happen that it is indicated that you suffer from some disease, mainly of the liver type. Normally, the alteration of these levels is related to certain pathologies, especially when you have the high transaminases.
It is always convenient to know your level of transaminases, because these enzymes are very important for the body’s metabolism to function properly.
Types of transaminases and meaning of their levels
Within the transaminases we can speak of several types: the GOT or AST, the GPT or ALT and the GGT. Now, we are going to go into more detail about each of them:
- GOT or glutamic-oxalacetic transaminase, which is also known as AST, is in most organs of the human body, although it is mostly concentrated in the liver. In addition, its presence is also significant in muscles and red blood cells. In general, when these transaminases are high it is indicated that a cellular destruction has been generated.
- GPT or glutamic-pyruvic transaminase, known as alanine aminotransferase or ALT, is in the liver and kidneys. To a lesser extent, it is located in the muscles and red blood cells. Its role in the human body is to make glucose. Such an alteration is related to glucose problems in the body, such as diabetes.
- GGT transaminase or gamma glutamyl transpeptidase it is the one that is more present in more parts of the body. In fact, it is also found in the pancreas, spleen, heart, brain, and kidneys, among others. Its high blood levels are often associated with diseases of the liver, pancreas or some or all of the bile duct mainly.
Normal blood transaminase levels
As always when talking about blood tests, there may be some variations in the results depending on the clinical laboratory that performed the analysis. However, as a guide, we can talk about a series of normal values of transaminases based on their type:
- GOT transaminases they are within normality when the analysis reflects a level between 0 and 37 units per liter.
- GPT transaminases they have normal values when they are between 0 and 41 units per liter.
- GGT transaminases show adequate parameters when they are between 11 and 50 units per liter.
Diseases related to high transaminase levels
In this way, a alteration of normal transaminase values it would be indicating that something is not working well in the body. In general, diseases produce a higher level of GPT or ALT transaminases than GOT or AST. The latter, the GOT or AST transaminases, when they double or triple the ALT level, indicate a liver problem related to alcohol intake.
In addition, when ALT and AST transaminases are high and more than ten times higher than normal, it is a sign of hepatitis or acute liver inflammation.
Causes of changes in normal transaminase levels
Although the alteration of the level of transaminases, especially when there is high transaminases, is related to diseasesThere are situations in which they rise for reasons that have nothing to do with any disease.
This is especially the case with GGT, since it is common for pregnant women have high levels of GGT, mainly when they are in the third trimester of pregnancy. Also children can give higher GGT values and be within normality. This occurs because the placenta and the growing bone mass cause levels to be higher in a normal way than those that we have discussed as standards.
From UNCOMO we hope that we have explained to you well what the normal levels of transaminases are and thus helped to make a first reading of the blood tests. However, do not forget to ask your doctor all the doubts you have and to show him the analytics to rule out that you have any disease or he can prescribe the appropriate treatment.
This article is merely informative, at oneHOWTO we do not have the power to prescribe any medical treatment or make any type of diagnosis. We invite you to see a doctor in the case of presenting any type of condition or discomfort.
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